Acremines A–F, novel secondary metabolites produced by a strain of an endophytic Acremonium, isolated from sporangiophores of Plasmopara viticola in grapevine leaves

• DOI: 10.1016/j.tet.2005.05.094
• Publication Date: 2005-06-20T20:04:21Z
• Authors: Gemma Assante; Sabrina Dallavalle; Luciana Malpezzi; Gianluca Nasini; Santella Burruano; Livio Torta
• Keywords: Plasmopara viticola; Acremonium; Strain (injury); Heteronuclear molecule

Six novel metabolites, acremines A-F have been isolated from agar cultures of a strain of Acremonium sp. Their structures and stereochemistry were elucidated using a combination of 13 C and H-1 homo and heteronuclear 2D NMR experiments and X-ray analysis. Acremines A-D inhibited the germination of sporangia of Plasmopara viticola.