Target-oriented multifunctional organocatalysis for enantioselective synthesis of bicyclo[3.3.1]nona-2,6-dien-9-ones. A formal asymmetric synthesis of huperzine A

• DOI: 10.1016/j.tet.2012.05.061
• Publication Date: 2012-05-23T22:11:31Z
• Authors: Xiao-Hua Ding; Xiang Li; Dan Liu; Wei-Chen Cui; Xuan Ju; Shaozhong Wang; Zhu-Jun Yao
• Keywords: Huperzine A

AbstractA new organocatalytic enantioselective Michael addition of α‐aryl‐β‐ketoesters to unsaturated aldehydes affords bicyclononadienones under mild conditions.