Copper-mediated synthesis of α-trifluoromethylthio- and seleno-α,β-unsaturated carbonyl compounds

• DOI: 10.1016/j.tet.2013.11.093
• Publication Date: 2013-12-03T11:07:02Z
• Authors: Peitao Zhu; Xing He; Xiaoqing Chen; Yi You; Yaofeng Yuan; Zhiqiang Weng
• Keywords: 01 natural sciences; 0104 chemical sciences; 3. Good health

A novel route to the synthesis of α-trifluoromethylthio- and seleno-α,β-unsaturated carbonyl compounds via a copper-mediated trifluoromethylthiolation/trifluoromethylselenolation of α-halo-α,β-unsaturated carbonyl substrates is reported.