Pd(OAc)2-catalyzed C–H activation of indoles: a facile synthesis of 3-cyanoindoles

• DOI: 10.1016/j.tetlet.2010.04.086
• Publication Date: 2010-04-26T04:37:45Z
• Authors: B.V. Subba Reddy; Zubeda Begum; Y. Jayasudhan Reddy; J.S. Yadav
• Keywords: Cyanation

AbstractThe novel protocol allows the direct cyanation of indoles through C—H bond activation to give the C‐3 substituted derivatives regioselectively.They represent potential materials in drug synthesis and precursors of natural products.