Leucomidines A–C, novel alkaloids from Leuconotis griffithii

• DOI: 10.1016/j.tetlet.2011.12.116
• Publication Date: 2012-01-03T23:54:51Z
• Authors: Midori Motegi; Alfarius Eko Nugroho; Yusuke Hirasawa; Takashi Arai; A.Hamid A. Hadi; Hiroshi Morita
• Keywords: Quinazoline; Indole alkaloid

Abstract Two novel indole alkaloids and new quinazoline alkaloids, namely leucomidines A–C ( 1–3 ), were isolated from the barks of Leuconotis griffithii . The structures including the absolute configuration were elucidated on the basis of spectroscopic data, chemical means, and CD calculations. The quinazoline alkaloid, 3 , is proposed to be derived from the same biogenetic precursor as the indole alkaloids 1 and 2 .