Synthesis of spiro 3-bromo-4,5-dihydroisoxazoles via [1,3]dipolar cycloaddition reactions

• DOI: 10.1016/j.tetlet.2015.02.006
• Publication Date: 2015-02-16T17:34:15Z
• Authors: Ebrahim Soleimani; Hossein Yazdani; Parisa Saei
• Keywords: 01 natural sciences; 0104 chemical sciences

Abstract A group of novel 4-bromo-7,9-dimethyl-1-aryl-2-oxa-3,7,9-triaza-spiro[4.5]dec-3-ene-6,8,10-trione derivatives is prepared through 1,3-dipolar cycloadditions between benzylidenes and bromonitrile oxide. This reaction is shown to have high atom economy.