Copper-catalyzed carbochlorination or carbobromination via radical cyclization of aryl amines

• DOI: 10.1016/j.tetlet.2016.02.054
• Publication Date: 2016-02-16T14:10:52Z
• Authors: Jianing Ouyang; Xiaolong Su; Yu Chen; Yaofeng Yuan; Yi Li
• Keywords: 01 natural sciences; 0104 chemical sciences

AbstractThe new and efficient copper‐catalyzed intramolecular carbochlorination employs aryl amines as starting materials and aqueous HCl, providing a facile access to relevant 3‐chloromethyl‐2,3‐dihydrobenzofuran derivatives.