Dimethyl malonate/LHMDS system as a new protocol for generating methyl formate anion (−COOMe) in the condensed-phase

• DOI: 10.1016/j.tetlet.2016.02.090
• Publication Date: 2016-02-28T19:06:18Z
• Authors: Valeria Di Bussolo; Salvatore Princiotto; Elisa Martinelli; Vittorio Bordoni; Paolo Crotti
• Keywords: Malonate; Dimethyl malonate; Anhydrous; Methyl formate; Carbocation

AbstractTreatment of dimethyl malonate with LiN(Tms)2 generates the expected lithium enolate and methyl formate anion.