Visible-light photoredox-promoted desilylative allylation of α-silylamines: An efficient route to synthesis of homoallylic amines

• DOI: 10.1016/j.tetlet.2021.153357
• Publication Date: 2021-08-27T09:21:55Z
• Authors: Lulu Fan; Fukun Cheng; Tingting Zhang; Guoxing Liu; Jinwei Yuan; Pu Mao
• Keywords: Reaction conditions

Abstract A facile and efficient synthesis of homoallylic amines by visible-light photoredox-promoted desilylative allylation of α-silylamines with allylic sulfones is described. A variety of α-silylamines derived from anilines, cyclic and acyclic alkyl amines reacted with a serious of mono or disubstituted allylic sulfones well to provide homollylic amines in good to high yields under very mild reaction conditions.