In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus

• DOI: 10.1016/j.toxcx.2022.100118
• Publication Date: 2022-03-18T07:08:07Z
• Authors: Stefanie K. Menzies; Rachel H. Clare; Chunfang Xie; Adam Westhorpe; Steven R. Hall; Rebecca J. Edge; Jaffer Alsolaiss; Edouard Crittenden; Amy E. Marriott; Robert A. Harrison; Jeroen Kool; Nicholas R. Casewell
• Keywords: Antivenom; Bothrops

Snakebite envenoming affects more than 250,000 people annually in sub-Saharan Africa. Envenoming by