Pascalia glauca poisoning in ruminants: Report of 12 outbreaks in northwestern Argentina

• DOI: 10.1016/j.toxicon.2022.05.040
• Publication Date: 2022-05-25T21:44:40Z
• Authors: Diego M. Medina; Laura S. Aguirre; Raul E. Marin; Juan F. Micheloud
• Keywords: Centrilobular necrosis

Pascalia glauca, a perennial herb known for its toxicity in ruminants, is one of the most important toxic plants in northwestern Argentina. This work describes several outbreaks of natural intoxication with P. glauca from different sources affecting cattle, sheep and goats in different production systems, with morbidity varying between 1% and 100%. Clinical signs included tremors in the hindquarters, recumbency and death. The liver showed swelling, congestion and a mottled appearance. Histopathologic findings included centrilobular hepatocellular necrosis with hemorrhage.