Exposure to radio-frequency electromagnetic waves alters acetylcholinesterase gene expression, exploratory and motor coordination-linked behaviour in male rats

• DOI: 10.1016/j.toxrep.2017.09.007
• Publication Date: 2017-10-04T06:30:23Z
• Authors: Adejoke Olukayode...; Ayodele Jacob Aki...; Olakunle Bamikole...; Khalid Adekoya; Joseph Olurotimi ...; Azeez Olakunle Is...
• Keywords: 0301 basic medicine; QP Physiology; 0303 health sciences; 03 medical and health sciences; RA1190-1270; Toxicology. Poisons; Q Science (General); QH426 Genetics; QM Human anatomy; Article

Humans in modern society are exposed to an ever-increasing number of electromagnetic fields (EMFs) and some studies have demonstrated that these waves can alter brain function but the mechanism still remains unclear. Hence, this study sought investigate effect 2.5 Ghz band radio-frequency (RF-EMF) exposure on cerebral cortex acetylcholinesterase (AChE) activity their mRNA expression level as well locomotor anxiety-linked behaviour male rats. Animals were divided into four groups namely; group 1 was control (without exposure), 2-4 radiofrequency from installed WI-FI device for a period 4, 6 8 weeks respectively. The results revealed WiFi caused significant increase anxiety affect function. Furthermore, there decrease AChE with concomitant rats when compared control. In conclusions, data showed long term may lead adverse effects such neurodegenerative diseases observed by alteration gene neurobehavioral parameters associated damage.