Bladder Agenesis and Bilateral Ectopic Ureters in an Infant Male With Cystic Renal Dysplasia, Imperforate Anus, and Penoscrotal Transposition

• DOI: 10.1016/j.urology.2021.02.032
• Publication Date: 2021-03-07T08:08:43Z
• Authors: Danly Omil-Lima; Karishma Gupta; Megan Prunty; Eiichi A. Miyasaka; Emily L. Joyce; Christina Nguyen; Jessica H. Hannick
• Keywords: Male; Urinary Bladder; Infant, Newborn; 3. Good health; Anus, Imperforate; 03 medical and health sciences; 0302 clinical medicine; Urethral Diseases; Scrotum; Humans; Kidney Failure, Chronic; Abnormalities, Multiple; Ureter; Penis; Polycystic Kidney, Autosomal Recessive

Bladder agenesis is a rare congenital anomaly infrequently reported in the literature, with an incidence of 1/600,000 patients.1 Commonly associated with other fatal malformations, the condition is often incompatible with life.2 Prior reports estimate that over 90% of living children born with this malformation are female, owing to renal preservation resulting from low pressure drainage of urine into the vagina, uterus, and vestibule.3,4 Herein we report a rare case of an infant male born with penoscrotal transposition and end stage renal disease secondary to bilateral cystic renal dysplasia found to have concurrent bladder agenesis and bilateral ureteral ectopia.