A phase 2 randomized controlled dose-ranging trial of recombinant pertussis booster vaccines containing genetically inactivated pertussis toxin in pregnant women

• DOI: 10.1016/j.vaccine.2023.06.001
• Publication Date: 2023-06-15T16:50:23Z
• Authors: Thanyawee Puthanakit; Kulkanya Chokepha...; Surasith Chaithon...; Niranjan Bhat; Yuxiao Tang; Suvaporn Anugulru...; Chenchit Chayachinda; Sanitra Anuwutnavin; Keswadee Lapphra; Supattra Rungmaitree; Monta Tawan; Indah Andi-Lolo; Renee Holt; Librada Fortuna; Chawanee Kerdsomboon; Vilasinee Yuwaree; Souad Mansouri; Pham Hong Thai; Bruce L. Innis
• Keywords: Pertactin; Filamentous haemagglutinin adhesin; Booster dose; Whooping cough; Pertussis vaccine

Despite a decrease in infections caused by Bordetella pertussis due to COVID-19 pandemic, booster vaccination of pregnant women is still recommended protect newborns. Highly immunogenic vaccines containing genetically inactivated toxin (PT