What determines mpox vaccination uptake? Assessing the effect of intent-to-vaccinate versus other determinants among men who have sex with men

• DOI: 10.1016/j.vaccine.2023.12.018
• Publication Date: 2023-12-09T06:07:47Z
• Authors: Vita W. Jongen; Marije L. Groot B...; Anders Boyd; Jeffrey C.D. Koole; Buhari Teker; Nicole H.T.M. Duk...; Ymke J. Evers; Maarten F. Schim ...; Maria Prins; Henry J.C. de Vries; Amy Matser; Udi Davidovich
• Keywords: Men who have sex with men; Vaccination; 610; Intention; Monkeypox; Smallpox Vaccine

In response to the mpox outbreak, vaccination was offered in Netherlands men who have sex with (MSM) at increased risk for mpox. Successful campaigns are leveraged by high intent-to-vaccinate, yet intent might not always lead uptake. Therefore, we assessed impact of intent-to-vaccinate and other factors on uptake among participants Amsterdam Cohort Studies (ACS). July 2022, prior campaign, distributed an online survey regarding as well e.g. beliefs, attitude, subjective norms, perception ACS (all MSM). Vaccination self-reported during study visits after August 2022. The association between uptake, determinants intent, jointly using a structural equation model (SEM) based components Theory Planned Behavior (TPB). second SEM, were allowed direct effect 492 MSM (median age = 46 years) included analyses. 380 (77%) had 238 (48%) received least one vaccine dose. first relation only, TBP predicted expected, significantly associated getting vaccinated (β 1.1, 95%CI 0.6–1.5). However, 175/380 (46%) did get vaccinated. improved fit compared model. non-significant, only perceiving be higher infection later 0.42, 0.26–0.59). Having steady relationship decreased probability -0.59, -1.0- −0.18). While MSM, necessarily result Mpox played more pivotal role vaccinated, which may related evolution eligibility criteria accessibility vaccine.