Probability of exposure to the wild measles virus in adult population – Estimation from seroepidemiology and historical data

• DOI: 10.1016/j.vaccine.2024.02.005
• Publication Date: 2024-02-10T06:10:31Z
• Authors: Jana Zibolenová; Eva Malobická; Romana Ulbrichtová; Martin Novák; Zuzana Chladná; Iveta Waczulíková; Slávka Litvová; Ján Mikas; Adriana Mečochová; Henrieta Hudečková
• Keywords: Herd Immunity; Morbillivirus

Vaccination against measles is one of the most effective public health interventions which has saved millions lives and interrupted circulation natural virus in population. However, it widely accepted that immunity after vaccination can wane, especially those who have had no contact with virus. This study aimed to classify particular birth cohorts adults regard their exposure wild population a long history mandatory vaccination. We introduced two methods. In first, we estimated probability through an analysis antibody levels from Immunologic Survey performed Slovak Republic 2018, while second was based on historical epidemiological data. Both methods resulted similar estimations. Cohorts born Slovakia before 1964 be considered people were exposed 1977 designated as likely did not come into between 1965 1976 are composed mixture, decreasing proportion increasing year birth. The proposed help identify potential gaps adult They applied other countries high coverage estimate cohorts.