Detection and modeling of anti-Leptospira IgG prevalence in cats from Lisbon area and its correlation to retroviral infections, lifestyle, clinical and hematologic changes

• DOI: 10.1016/j.vas.2020.100144
• Publication Date: 2020-10-01T08:46:35Z
• Authors: Joana Moreira da ...; Sara Prata; Tiago Dias Domingues; Rodolfo Oliveira ...; Telmo Nunes; Luís Tavares; Virgílio Almeida; Nuno Sepúlveda; Solange Gil
• Keywords: Seroprevalence; Zoonosis

Leptospirosis is a zoonosis of global importance caused by Leptospira species. Rodents are the main reservoirs, known to shed bacteria in urine, thus contaminating water and soil infecting other animals people. has been re-emerging both developing developed countries including Europe. It hypothesized that cats could be asymptomatic carriers Leptospira. This study aims evaluate cats' exposure Lisbon, Portugal, measuring IgG titres correlating them with possible factors may increase risk urban cats. Two hundred forty-three samples were collected from biobank. An ELISA test followed seroprevalence analysis using finite mixture model was performed detect measure anti-Leptospira antibodies titres. In parallel, survey conducted identify for seropositivity. According protocol, only twenty-three (9.5%; 95% CI =(6.1%;13.9%)) considered as seropositive antigens. However, when same data analysed best different models, one forty-four (59.3%; 95%CI = (52.8%; 65.5%)) classified intermediate high antibody responders Seropositivity Feline Immunodeficiency Virus infection (FIV) found significant factor associated antibodies. conclusion, present studies raises possibility higher than previously thought due identification subpopulation levels.