Association of dementia with clinical and financial outcomes following lobectomy for lung cancer

• DOI: 10.1016/j.xjon.2023.09.019
• Publication Date: 2023-09-22T16:30:33Z
• Authors: Konmal Ali; Sara Sakowitz; Nikhil L. Chervu; Arjun Verma; Syed Shahyan Bakh...; Joanna Curry; Nam Yong Cho; Peyman Benharash

ObjectiveThe number of adults with dementia is rising worldwide. Although has been linked inferior outcomes following various operations, this phenomenon not fully elucidated among patients undergoing elective lung resection. Using a national cohort, we evaluated the association clinical and financial lobectomy for cancer.MethodsAdults cancer were identified within 2010-2020 Nationwide Readmissions Database. Patients comorbid diagnosis considered Dementia cohort (others: Non-Dementia). Multivariable regressions developed to evaluate between key outcomes.ResultsOf ∼314,436 patients, 2863 (0.9%) comprised cohort. Compared Non-Dementia, was older (75 vs 68 years, P < .001), less commonly female (49.4 53.9%, = .01), had greater burden conditions. After adjustment, remained associated similar odds in-hospital mortality (adjusted ratio [aOR], 0.86; 95% confidence interval [CI], 0.54-1.38) but likelihood pneumonia (aOR, 1.31; CI, 1.04-1.65) infectious complications 1.37; 1.01-1.87). Further, longer length stay (β +0.96 days; 0.51-1.41), no difference in hospitalization cost $1528; −92 3148).ConclusionsPatients faced mortality, resource use cancer. Novel interventions are needed improve care coordination develop standardized recovery pathways growing cohort.Graphical abstract