Protocol for phage matching, treatment, and monitoring for compassionate bacteriophage use in non-resolving infections

• DOI: 10.1016/j.xpro.2024.102949
• Publication Date: 2024-04-30T20:37:18Z
• Authors: Hadil Onallah; Ortal Yerushalmy; Ron Braunstein; Sivan Alkalay-Oren; Amit Rimon; Daniel Gelman; Shunit Coppenhage...; Ronen Hazan; Ran Nir-Paz
• Keywords: Phage therapy; Compassionate Use

Phage therapy has re-emerged as a promising treatment for non-resolving infections. Given the lack of approved phage treatments, there is need to establish compassionate use pipeline. Here, we present protocol matching, treatment, and monitoring bacteriophage in We describe steps consultation request implementation, evaluating comparing different aspects activity, production. then detail procedures multidisciplinary meetings, ethics approvals, therapy, follow-up. For complete details on execution this protocol, please refer Onallah et al.1,2