A new strategy for directed protein cleavage

• DOI: 10.1016/s0040-4039(00)91569-7
• Publication Date: 2002-07-25T20:24:28Z
• Authors: Bernard Cuenoud; Theodore M. Tarasow; Alanna Schepartz
• Keywords: 01 natural sciences; 0104 chemical sciences

Abstract Attachment of a Ni(II)-glyglyhis chelate to trifluoperazine results in a molecule capable of cleaving calmodulin at a single locus upon activation with a peracid.