Shorter Reperfusion Time in Stroke is Associated with Better Cognition

• DOI: 10.1017/cjn.2023.321
• Publication Date: 2023-12-06T03:36:50Z
• Authors: Joana Costa Novo; Evelyne Rieffel; Guillermo Coca Ve...; Francisca Costa; Pedro Barros; Miguel Veloso; Henrique Costa; Ludovina Paredes; Tiago Gregório; Marta Rodrigues; Pedro Calvão-Pires; Ana Campolargo; Valéria Battistella
• Keywords: Interquartile range; Stroke

ABSTRACT: Background: Cognitive changes that result from cerebrovascular disease contribute to a poor functional outcome with reduced quality of life. Among patients undergoing endovascular therapy (EVT), we aim assess cognitive function and evaluate the impact reperfusion time in performance. Methods: Patients acute right anterior circulation strokes underwent EVT between January 2018 August 2020 at Centro Hospitalar de Vila Nova Gaia/Espinho, participated study. Modified treatment cerebral infarction (mTICI) assessed level recanalization. evaluation was Addenbrooke’s Examination revised (ACE-R). Multiple linear regression analyses were used determine association for recanalization ACE-R. The significance adopted 0.05. Results: mean age participants 71.5 (interquartile range [IQR] 62.0–78.2) years, 50% (22) women. median after stroke 28.6 months (IQR 18.94–31.55). All our sample had successful (mTICI ≥ 2b). Time showed an inverse ACE-R ( b = −0.0207, P 0.0203). Also mRS 3 cognition −5.2803, p 0.0095). Level education strong direct relationship results 3.0869, < 0.0001). Conclusions: Longer symptoms hemisphere ischemic lead lower scores. Measures improve door-to-recanalization are also important performance stroke.