Estimating the cost of inappropriate antibiotic prophylaxis prior to dental procedures

• DOI: 10.1017/ice.2023.126
• Publication Date: 2023-07-10T06:31:41Z
• Authors: Cynthia L. Gong; Anh Duong; Kenneth M. Zangwill
• Keywords: Endocarditis; Dentistry; Humans; Amoxicillin; Endocarditis, Bacterial; Antibiotic Prophylaxis; United States; 3. Good health; Anti-Bacterial Agents

AbstractInappropriate dental antibiotic prescriptions to prevent infective endocarditis in the United States results in ∼$31 million in excess costs to the healthcare system and patients. This includes out-of-pocket costs ($20.5 million), drug costs ($2.69 million) and adverse event costs (eg, Clostridioides difficile and hypersensitivity) of $5.82 million (amoxicillin), $1.99 million (clindamycin), and $380,849 (cephalexin).