Catheter-associated urinary tract infections (CAUTIs) and non-CAUTI hospital-onset urinary tract infections: Relative burden, cost, outcomes and related hospital-onset bacteremia and fungemia infections

• DOI: 10.1017/ice.2024.26
• Publication Date: 2024-02-20T07:12:58Z
• Authors: Timothy Kelly; ChinEn Ai; Molly Jung; Kalvin Yu
• Keywords: Bacteremia; Fungemia

Abstract Objective: To describe the relative burden of catheter-associated urinary tract infections (CAUTIs) and non-CAUTI hospital-onset (HOUTIs). Methods: A retrospective observational study patients from 43 acute-care hospitals was conducted. CAUTI cases were defined as those reported to National Healthcare Safety Network. Non-CAUTI HOUTI a positive, non-contaminated, non-commensal culture collected on day 3 or later. All HOUTIs required have new antimicrobial prescribed within 2 days first positive urine culture. Outcomes included secondary bacteremia fungemia (HOB), total hospital costs, length stay (LOS), readmission risk, mortality. Results: Of 549,433 admissions, 434 CAUTIs 3,177 observed. The overall rate HOB likely 3.7%. Total numbers higher in compared (101 vs 34). more originate outside ICU (69.3% 44.1%). associated with adjusted incremental cost LOS $9,807 ( P < .0001) 3.01 while $6,874 2.97 .0001). Conclusion: deleterious outcomes. occurred often facility aggregate volume than CAUTI. Patients at risk for UTIs represent vulnerable population who may benefit surveillance prevention efforts, particularly non-ICU setting.