A pulse-based diet is effective for reducing total and LDL-cholesterol in older adults

• DOI: 10.1017/s0007114512000748
• Publication Date: 2012-08-23T12:49:20Z
• Authors: Saman Abeysekara; Philip D. Chilibeck; Hassanali Vatanpa...; Gordon A. Zello
• Keywords: Male; 2. Zero hunger; 0303 health sciences; Cross-Over Studies; Fabaceae; Cholesterol, LDL; Middle Aged; Diet; 3. Good health; 03 medical and health sciences; Cholesterol; Cardiovascular Diseases; Risk Factors; Seeds; Body Composition; Humans; Female; Single-Blind Method

Our purpose was to determine the effects of a pulse-based diet in individuals 50 years or older for reducing CVD risk factors. A total of 108 participants were randomised to receive pulse-based foods (two servings daily of beans, chickpeas, peas or lentils; about 150 g/d dry weight) or their regular diet for 2 months, followed by a washout of 1 month and a cross-over to the other diet for 2 months. Anthropometric measures, body composition and biochemical markers (i.e. serum LDL-cholesterol (LDL-C), as the primary outcome, and other lipids, glucose, insulin and C-reactive protein) were assessed before and after each diet phase. A total of eighty-seven participants (thirty males and fifty-seven females; 59·7 (sd6·3) years, body mass 76 (sd16) kg) completed the study. Compared with the regular diet, the pulse-based diet decreased total cholesterol by 8·3 % (pulse, 4·57 (sd0·93) to 4·11 (sd0·91) mmol/l; regular, 4·47 (sd0·94) to 4·39 (sd0·97) mmol/l;P < 0·001) and LDL-C by 7·9 % (pulse, 2·93 (sd0·84) to 2·55 (sd0·75) mmol/l; regular, 2·96 (sd0·86) to 2·81 (sd0·83) mmol/l;P = 0·01). In a sub-analysis of individuals with high lipid levels at baseline (twenty individuals with high cholesterol), the pulse-based diet reduced cholesterol by 6 % compared with the regular diet (pulse, 5·62 (sd0·78) to 5·26 (sd0·68) mmol/l; regular, 5·60 (sd0·91) to 5·57 (sd0·85) mmol/l;P = 0·05). A pulse-based diet is effective for reducing total cholesterol and LDL-C in older adults and therefore reduces the risk of CVD.