In vitrolipolysis and lymphatic absorption ofn-3 long-chain PUFA in the rat: influence of the molecular lipid species as carrier

• DOI: 10.1017/s0007114519001491
• Publication Date: 2019-06-24T08:46:46Z
• Authors: Anthony Sehl; Leslie Couëdelo; Ikram Chamekh-Coelho; Carole Vaysse; Maud Cansell
• Keywords: Digestion; Lipid digestion; Chylomicron

Abstract The aim of this work was to study the bioavailability fatty acids (FA), focusing on n -3 long-chain (LC) PUFA, carried by different molecular lipid species, that is, phospholipids (PL) or TAG, with three formulations based fish oils marine PL, providing a similar LC PUFA amount. digestive lipolysis first assessed using an in vitro enzymatic model. Then, intestinal absorption and enterocyte metabolism were investigated vivo , male Wistar rats through lymph analysis. results showed release from increased 48 % when FA provided as PL rather than TAG. demonstrated EPA DHA both TAG similarly absorbed incorporated into lipids. However, mainly distributed at sn -1/3 positions whereas it equally On whole, even if species did not greatly modify digestion steps, modulated rearrangement glyceride which may further impact metabolic fate tissue accretion. Consequently, present has data be used formulate diets rich context insufficient consumption Western countries.