Reevaluation of the protein requirement in Chinese elderly adults without sarcopenia with the indicator amino acid oxidation technique

• DOI: 10.1017/s0007114523002611
• Publication Date: 2023-12-11T07:55:17Z
• Authors: Wenxuan Wu; Yanhong Zhang; Hui Ma; Jiaxi Lu; Fengge Chen; Haisong Zhou; Shuhui Nie; Yunqi Yang; Rui Wang; Weixiao Yue; Min Li; Lichen Yang
• Keywords: Resting energy expenditure; Energy requirement; Protein requirement

Abstract It is now generally believed that elderly may have slightly higher dietary protein requirements than those of the young-middle-aged adults. We previously conducted related studies by indicator amino acid oxidation (IAAO) technique, but more research data are needed to revise elderly. The main objective was reevaluate healthy Chinese adults (65–80 years) without sarcopenia using IAAO technique. Nine adult men and seven women participated in study, with intakes ranging from 0·1 1·8 g/(kg·d). Diets delivered energy at a 1·5 resting expenditure were isocaloric. amounts phenylalanine tyrosine remain constant for each dosage. By applying nonlinear mixed-effects model analysis on F 13 CO 2 data, which revealed breakpoint response graded intakes, mean requirement calculated. estimated average (EAR) determined be 0·94 recommended nutrient intake (RNI) various derivation approaches ranged 1·13 1·36 EAR aged 65–80 years this study 6·8 % current (0·88 g/(kg·d)). RNI derived all greater (0·98 This trial registered clinical registry as ChiCTR2200061382.