Molecular characterization ofCryptosporidium parvumisolates from human cryptosporidiosis cases in Scotland

• DOI: 10.1017/s0031182014001346
• Publication Date: 2014-09-23T08:18:28Z
• Authors: A. P. DESHPANDE; B. L. JONES; L. CONNELLY; K. G. POLLOCK; S. BROWNLIE; C. L. ALEXANDER
• Keywords: Cryptosporidium parvum; Subtyping; Human feces

SUMMARY Cryptosporidium parvum ( C. ) is one of the most prevalent protozoan pathogens responsible for inducing human and animal disease worldwide. In this study, glycoprotein-60 (gp60) subtyping tool was employed to assess molecular diversity from feces throughout Scotland during potential outbreaks. Over a 24-month period, microscopy analysis revealed 1139 positive containing species with 256 identified by methods specifically as parvum. shown be more in rural areas 87 isolates demonstrated predominant family IIa, which occurred 94% n = 82) isolates. The IIaA15G1R1 subtype common, being isolated 47% 41) Scottish cases. Non-IIa strains constituted total 5 included subtypes IIc, IId IIg families. This information contributes significantly existing knowledge understanding vital assisting management future local national