Guillain-Barré syndrome outbreak in Tapachula temporally associated with the Zika virus introduction in Southern Mexico

• DOI: 10.1017/s0950268822001625
• Publication Date: 2022-10-19T06:42:00Z
• Authors: Ricardo Paul Rodr...; J. Oggún Cano-Torres; Sonia Rosales; Anke Paula Kleinert; Arturo Gómez; Fernando George; José George; Mariana Piedad Ga...; Gabriel Nájera-Ca...; Paola del Carmen ...; Pablo F Belaunzar...; John Beigel; Guillermo Miguel ...
• Keywords: Zika Virus; Microcephaly

Abstract The Guillain-Barré syndrome (GBS) has been previously associated with Zika virus infection. We analysed the data from all patients GBS diagnosis that were admitted to a referral hospital, in Tapachula City during period January 2013 August 2016, comparing incidence of according temporality outbreak Southern Mexico. Additionally, we described clinical and epidemiological characteristics before or after outbreak. observed sharp increase number hospitalised due time first confirmed cases appeared Clinically zika had more frequently history respiratory/gastrointestinal symptoms significantly recent rash/conjunctivitis. Although cannot affirm increased have specific aetiologic association Zika, our results suggest this Tapachula, might emerging epidemic, locally suggests rare complications acute infections (such as GBS) be useful surveillance systems for infections.