Optimism and risk of incident hypertension: a target for primordial prevention

• DOI: 10.1017/s2045796020000621
• Publication Date: 2020-08-14T11:26:53Z
• Authors: Laura D. Kubzansky; Julia K. Boehm; Andrew R. Allen; Loryana L. Vie; Tiffany E. Ho; Claudia Trudel-Fi...; Hayami K. Koga; Lawrence M. Scheier; Martin E. P. Seli...
• Keywords: Prehypertension

Optimism is associated with reduced cardiovascular disease risk; however, few prospective studies have considered optimism in relation to hypertension risk specifically. We investigated whether was a lower of developing U.S. service members, who are more likely develop high blood pressure early life. also evaluated race/ethnicity, sex and age as potential effect modifiers these associations.Participants were 103 486 hypertension-free Army active-duty soldiers (mean 28.96 years, 61.76% White, 20.04% Black, 11.01% Hispanic, 4.09% Asian, 3.10% others). assessed optimism, sociodemographic characteristics, health conditions, behaviours depression status at baseline (2009-2010) via self-report administrative records, ascertained incident over follow-up (2010-2014) from electronic records assessments. used Cox proportional hazards regression models estimate hazard ratios (HRs) 95% confidence intervals (CIs), adjusted for broad range relevant covariates.Over mean 3.51 15 052 cases occurred. The highest v. lowest levels 22% hypertension, after adjusting all covariates including (HR = 0.78; CI 0.74-0.83). difference between the maintained when we excluded first two years and, separately, prehypertension baseline. A dose-response relationship evident higher relative (p < 0.001). Higher consistently across sex, most race/ethnicity categories.In diverse cohort initially healthy male female members particularly vulnerable independently factors, notable finding given young population. Results suggest asset target public interventions.