Investigation of the Initial Crystallization Stage in Lysozyme Solutions by Small-Angle X-ray Scattering

• DOI: 10.1021/acs.cgd.5b01662
• Publication Date: 2016-02-23T20:05:34Z
• Authors: Mikhail V. Kovalchuk; Alexander E. Blagov; Yulia A. Dyakova; Andrey Yu. Gruzinov; Margarita A. Marc...; Georgy S. Peters; Yury V. Pisarevsky; Vladimir I. Timofeev; Vladimir V. Volkov
• Keywords: Small-angle X-ray scattering; Histone octamer; Tetragonal crystal system; Small-Angle Scattering; Crystal (programming language)

From the base structure of tetragonal lysozyme crystals, octamer cluster was selected as possible element crystal growth. The proposed model verified by small-angle X-ray scattering (SAXS) measurements solutions. results showed a noticeable presence dimers and octamers under crystallization conditions total absence oligomers where growth impossible.