Association between Several Persistent Organic Pollutants in Serum and Adipokine Levels in Breast Milk among Lactating Women of Korea

• DOI: 10.1021/acs.est.5b00520
• Publication Date: 2015-06-09T10:40:43Z
• Authors: Sunmi Kim; Jeongim Park; Hai-Joong Kim; Jeong Jae Lee; Gyuyeon Choi; Sooran Choi; Sungjoo Kim; Su Young Kim; Duk Hee Lee; Hyo-Bang Moon; Sungkyoon Kim; Kyungho Choi
• Keywords: Adult; Leptin; 2. Zero hunger; Milk, Human; Environmental Exposure; Middle Aged; Lipid Metabolism; Polychlorinated Biphenyls; 01 natural sciences; DDT; 3. Good health; Breast Feeding; Adipokines; Chlordan; Pregnancy; 13. Climate action; Republic of Korea; Humans; Environmental Pollutants; Female; Adiponectin; Hexachlorocyclohexane; 0105 earth and related environmental sciences

Exposure to several persistent organic pollutants (POPs) has been linked alteration of lipid metabolism. Adipokines, such as leptin and adiponectin, are hormones that play roles in metabolism, have suggested markers health effects may lead obesity. To date, only serum adipokines associated with POPs exposure. In the present study, for first time, associations between adiponectin breast milk, were investigated among 82 lactating Korean women 25 46 years age. Breast milk important because adipokine intake infant through breastfeeding influence growth infants. The median concentrations skimmed 17.9 ng/L 16.5 μg/L, respectively. Leptin negatively ∑hexachlorohexane (HCH), oxychlordane, ∑chlordane, or 2,2′,4,4′,5,5′-hexachlorobiphenyl (CB 153) levels maternal serum. Linear relationships not observed, however, nonmonotonic relationship which showed generally positive was p,p′-dichlorodiphenyltrichloroethane (DDT) ∑chlordane quartile analysis. Our observations show at current level exposure be metabolism women. Implication transfer breastfed infants is concern deserves further investigation.