Zinc Supplementation Alleviates Lipid and Glucose Metabolic Disorders Induced by a High-Fat Diet

• DOI: 10.1021/acs.jafc.0c01103
• Publication Date: 2020-04-15T02:50:26Z
• Authors: Yilin Qi; Zhiwang Zhang; Siqi Liu; Zhier Aluo; Lifang Zhang; Lin Yu; Yixing Li; Ziyi Song; Lei Zhou
• Keywords: Steatosis; Carbohydrate Metabolism; Metabolic disorder

Zinc deficiency is a risk factor for the development of obesity and diabetes. Studies have shown lower serum zinc levels in obese individuals those with We speculate that supplementation can alleviate diabetes and, to some extent, their complications. To test our hypothesis, we investigated effects on mice high-fat diet (HFD)-induced hepatic steatosis vivo vitro by adding medium HepG2 cells. Both results showed high could glucose lipid metabolic disorders induced HFD. High reduce production, promote absorption, deposition, improve HFD-induced liver injury, regulate energy metabolism. This study provides novel insight into treatment non-alcoholic fatty disease disorder.