Human Exposure of Fipronil Insecticide and the Associated Health Risk

• DOI: 10.1021/acs.jafc.1c05694
• Publication Date: 2021-12-31T15:49:07Z
• Authors: Dawei Chen; Jingguang Li; Yunfeng Zhao; Yongning Wu
• Keywords: Insecticides; Humans; Pyrazoles; 01 natural sciences; 3. Good health; 0104 chemical sciences; 0105 earth and related environmental sciences

Fipronil, as an emerging phenylpyrazole insecticide, is ubiquitous in the environment and food due to its broad spectrum and persistent characteristics, but the research on pathways of human exposure to fipronil and the associated health risk is relatively unclear. In this regard, we summarize potential human exposures to fipronil through ingestion and inhalation, as well as results of human biomonitoring studies. This scientific information will contribute to future assessment of fipronil exposure and subsequent characterization of human health risks. Additionally, this Perspective highlights the lack of epidemiological studies and total diet studies for the general population on fipronil.