Comprehensive Analysis of Transcriptome and Metabolome Reveals Regulatory Mechanism of Intramuscular Fat Content in Beef Cattle

• DOI: 10.1021/acs.jafc.3c07844
• Publication Date: 2024-02-02T06:09:50Z
• Authors: Hengwei Yu; Shengchen Yu; Juntao Guo; Jianfang Wang; Chugang Mei; Sayed Haidar Abba...; Gong Cheng; Linsen Zan
• Keywords: Intramuscular fat; Metabolome; Beef Cattle; Korean Native; KEGG

The intramuscular fat (IMF) content of beef determined the meat quality, and market value varies with different breeds. To provide some new approaches for improving quality cattle breed improvement, 24-month-old Qinchuan (Q, n = 6), Nanyang (N, Japanese black (J, 6) were selected. IMF J group (16.92 ± 1.08%) is remarkably higher than that indigenous Chinese 13.38 1.08%, N, 12.35 1.22%). Monounsaturated fatty acids polyunsaturated in are Q creatine, lysine, glutamine three most abundant amino beef, which contribute to flavor formation. Similarly, content-related genes enriched four vital KEGG pathways, including acid metabolism, biosynthesis unsaturated acids, elongation, insulin resistance. Moreover, weighted coexpression network analysis (WGCNA) revealed ITGB1 critical gene associated content. This study compares transcriptome metabolome local high-IMF breeds, providing data native breeding improvement quality.