Coencapsulation of (−)-Epigallocatechin-3-gallate and Quercetin in Particle-Stabilized W/O/W Emulsion Gels: Controlled Release and Bioaccessibility

• DOI: 10.1021/acs.jafc.7b05161
• Publication Date: 2018-03-26T16:55:58Z
• Authors: Xing Chen; David Julian McCl...; Jian Wang; Liqiang Zou; Sumeng Deng; Wei Liu; Chi Yan; Yuqing Zhu; Ce Cheng; Chengmei Liu
• Keywords: Gallate; Particle (ecology)

Particle-stabilized W1/O/W2 emulsion gels were fabricated using a two-step procedure: (i) W1/O was formed containing saccharose (for osmotic stress balance) and gelatin (as gelling agent) in the aqueous phase polyglycerol polyricinoleate (a lipophilic surfactant) oil phase; (ii) this then homogenized with another water (W2) wheat gliadin nanoparticles (hydrophilic emulsifier). The external aggregated at pH 5.5, which led to formation of particle-stabilized good stability separation. These used coencapsulate hydrophilic bioactive (epigallocatechin-3-gallate, EGCG) internal (encapsulation efficiency = 65.5%) hydrophobic (quercetin) 97.2%). improved EGCG chemical quercetin solubility under simulated gastrointestinal conditions, 2- 4-fold increase their effective bioaccessibility, respectively.