Effects of Whole-Grain Rice and Wheat on Composition of Gut Microbiota and Short-Chain Fatty Acids in Rats

• DOI: 10.1021/acs.jafc.8b01891
• Publication Date: 2018-05-16T09:19:03Z
• Authors: Fei Han; Yong Wang; Yangyang Han; Jianxin Zhao; Fenli Han; Ge Song; Ping Jiang; Haijiang Miao
• Keywords: Short-chain fatty acid

Diets rich in whole grain (WG) cereals bring lower disease risks compared with refined grain-based diets. We investigated the effects of polished rice (PR), wheat (RW), unpolished (UPR), and (WW) on short-chain fatty acids (SCFAs) gut microbiota ileal, cecal, colonic digesta normal rats. Animals fed UPR WW diets exhibited higher total SCFA cecal those PR RW Wheat contributed than In digesta, animals demonstrated acetate butyrate contents given RW. Firmicutes were dominant eumycota rat ileum (>92% abundance). Cecal dominated by Firmicutes, Verrucomicrobia, Bacteroidetes. affected microbiota, decreasing proportion to SMB53, Lactobacillus, Faecalibacterium main bacterial genera ileal digesta. Akkermansia was highest rats, relative abundance rats that ( P < 0.05). Thus, could modulate composition increase concentration. diet superior terms intestinal adjustment.