Enhancement in Antibacterial Activities of Eugenol-Entrapped Ethosome Nanoparticles via Strengthening Its Permeability and Sustained Release

• DOI: 10.1021/acs.jafc.8b06278
• Publication Date: 2019-01-09T21:08:20Z
• Authors: Peng Jin; Rui Yao; Dingkui Qin; Qing Chen; Qizhen Du
• Keywords: Methyl eugenol

The antibacterial efficiency and synergistic mechanisms of novel formulated eugenol entrapped ethosome nanoparticles (ELG-NPs) against fruit anthracnose were investigated. results showed that concentrations ethanol significantly influenced the particle size entrapment nanoethosome, effect. Superior ELG-NPs with optimized process (0.5% eugenol, 2% lecithin, 30% ethanol) obtained a 44.21 nm 82%. exhibited an activity (>93%) pathogens was greater than free 100% inhibition incidence in postharvest loquat after 6 d. permeability study, first visualized banana cortex fluorescent indicators, demonstrated delivered to interior 6-fold higher eugenol. satisfactory slow-release prolonged action. This work provides promising strategy for disease controls agricultural, food, cosmetic, medical areas.