Thermodynamic Modeling of the Solubility and Preferential Solvation of the Natural Product Vanillic Acid in Some Aqueous Mixtures of Alcohols at Different Temperatures

• DOI: 10.1021/acs.jced.2c00178
• Publication Date: 2022-06-23T18:13:16Z
• Authors: Adel Noubigh; Manef Abderrabba
• Keywords: Vanillic acid; Gravimetric analysis; Propanol

The solid–liquid equilibrium of vanillic acid (3) in solvent mixtures 1-propanol (1) + water (2) and 2-propanol was estimated utilizing gravimetric method findings the temperature range 283.15–323.15 K. solvency depends on dissolvable mixtures, it determined through van't Hoff–Jouyban–Acree Apelblat–Jouyban–Acree models. Normal relative deviations lower than 3% root-mean-square 0.53 × 10–3 were obtained for reciprocal examinations. With solubility data this study results from our previous work, we particular criteria (δx1,3) a characteristic phenolic compound, acid, parallel combinations cosolvent (2). values δx1,3 changed nonlinearly with codissolvable dimension concentrated varied solvents. Vanillic especially solvated by water-rich compositions, whereas cosolvent-rich intermediate preferentially organic studied. as result its positive values. A estimate can be clarified high acidic behavior particles collaboration hydrogen acceptors organized cosolvent.