Photoinduced Cyclizations of o-Diisocyanoarenes with Organic Diselenides and Thiols that Afford Chalcogenated Quinoxalines

• DOI: 10.1021/acs.joc.0c00647
• Publication Date: 2020-04-29T09:22:42Z
• Authors: Cong Chi Tran; Shin-ichi Kawaguchi; Fumiya Sato; Akihiro Nomoto; Akiya Ogawa
• Keywords: Quinoxaline

This study describes the syntheses of 2,3-bis(selanyl)quinoxalines via photoinduced cyclizations o-diisocyanoarenes with diaryl or dialkyl diselenides, in addition to providing a detailed discussion corresponding mechanism and revealing that developed procedure can also be applied prepare 2-thiolated quinoxaline derivatives from thiols. The technique does not need use additives metal catalysts features advantages high conversion, broad substrate scope, mild reaction conditions, thereby rendering it valuable synthesis toolbox.