Divergent Reactivity of Iminyl Radicals in Four Interrupted Pathways for the Synthesis of Cyclic/Acyclic Ketones and N-Heterocycles from Vinyl Azides and Phenylacetic Acids

• DOI: 10.1021/acs.joc.4c01243
• Publication Date: 2024-09-11T18:53:28Z
• Authors: Swagota Paul; Ashitosh Baruah; Atul A. More
• Keywords: Reactivity; Radical cyclization; Phenylacetic acid

Herein, we report the Ag-catalyzed substrate-controlled interrupted radical pathways of iminyl radical. The benzylic groups played a crucial role in pathway selection involving series dimerization and hydrolysis, 1,5-H shift followed by cascade cyclization, direct N-(sp