CO2•– Enabled Synthesis of Phenanthridinones, Oxindoles, Isoindolinones, and Spirolactams

• DOI: 10.1021/acs.joc.4c02490
• Publication Date: 2025-03-01T03:05:01Z
• Authors: Vijay Kumar Simhadri; Rupam Sur; Veera Reddy Yatham

We report herein that photoinduced CO2•– enabled reductive intramolecular radical cyclization of a variety aryl iodide derivatives to the corresponding phenanthridinone, oxindole, isoindolinone, and spirolactam in good yields. Preliminary mechanistic studies suggested generation through homolysis cesium formate presence light, further involvement was directly proved by trapping with diphenyl styrene TEMPO.