Access to Spirocyclized Oxindoles and Indolenines via Palladium-Catalyzed Cascade Reactions of Propargyl Carbonates with 2-Oxotryptamines and Tryptamines

• DOI: 10.1021/acs.joc.5b00277
• Publication Date: 2015-04-15T12:52:19Z
• Authors: Antoinette E. Nibbs; Thomas D. Montgomery; Ye Zhu; Viresh H. Rawal
• Keywords: Indoles; Molecular Structure; Pargyline; Cyclization; Spiro Compounds; 01 natural sciences; Catalysis; Palladium; Tryptamines; Oxindoles; 0104 chemical sciences

AbstractA variety of the desired N‐heterocyclic scaffolds, required for alkaloid preparation, is best available by reaction of the educts with propargyl carbonate (II).