Inherently Chiral Azonia[6]helicene-Modified β-Cyclodextrin: Synthesis, Characterization, and Chirality Sensing of Underivatized Amino Acids in Water

• DOI: 10.1021/acs.joc.6b00130
• Publication Date: 2016-03-22T18:10:15Z
• Authors: Qinfei Huang; Liangwei Jiang; Wenting Liang; Jianchang Gui; Dingguo Xu; Wanhua Wu; Yoshito Nakai; Masaki Nishijima; Gaku Fukuhara; Tadashi Mori; Yoshihisa Inoue; Cheng Yang
• Keywords: Helicene; Chirality; Characterization

The (P)- and (M)-3-azonia[6]helicenyl β-cyclodextrins exhibit L/D selectivities of up to 12.4 P/M preferences 28.2 upon complexation with underivatized proteinogenic amino acids in aqueous solution at pH 7.3.