Use of (Cyclopentadienone)iron Tricarbonyl Complexes for C–N Bond Formation Reactions between Amines and Alcohols

• DOI: 10.1021/acs.joc.7b01990
• Publication Date: 2017-09-18T17:05:33Z
• Authors: Thomas J. Brown; Madeleine Cumbes; Louis J. Diorazio; Guy J. Clarkson; Martin Wills
• Keywords: Trimethylsilyl

The application of a series (cyclopentadienone)iron tricarbonyl complexes to "borrowing hydrogen" reactions between amines and alcohols was completed in order assess their catalytic activity. electronic variation the aromatic groups flanking C═O cyclopentadienone influenced efficiency reactions; however, other cases, Knölker catalyst 1, containing trimethylsilyl ketone, gave best results. In some change ratio amine alcohol improves conversion significantly. iron catalysts synthesis range amines, including unsaturated investigated.