Iron Ion and Iron Hydroxide Adsorption to Charge-Neutral Phosphatidylcholine Templates

• DOI: 10.1021/acs.langmuir.6b01851
• Publication Date: 2016-07-14T03:40:40Z
• Authors: Wenjie Wang; Honghu Zhang; Shuren Feng; Josue San Emeterio; Surya Mallapragada; David Vaknin
• Keywords: Surface charge

Surface-sensitive X-ray scattering and spectroscopy techniques reveal significant adsorption of iron ions iron-hydroxide (Fe(III)) complexes to a charge-neutral zwitterionic template phosphatidylcholine (PC). The PC is formed by Langmuir monolayer dipalmitoyl-PC (DPPC) that spread on the surface 2 40 μM FeCl3 solutions at physiological levels KCl (100 mM). At Fe(III) as many ∼3 atoms are associated with each group. Grazing incidence diffraction measurements indicate disruption in in-plane ordering DPPC molecules upon adsorption. binding neutral yet another example nonelectrostatic, presumably covalent bonding organic template. strong lipid structure has biological implications integrity PC-derived membranes, including those based sphingomyelin.