Multilayer Capsules Inside Biological Systems: State-of-the-Art and Open Challenges

• DOI: 10.1021/acs.langmuir.8b04280
• Publication Date: 2019-03-06T20:07:57Z
• Authors: Mikhail V. Zyuzin; Alexander S. Timin; Gleb B. Sukhorukov
• Keywords: Surface Modification; Capsule

There are many reports about the interaction of multilayer capsules with biological systems in literature. A majority them devoted to vitro study two-dimensional cell cultures. Multilayer capsule fabrication had been under intensive investigation from 1990s and 2000s by Prof. Helmuth Möhwald, his followers further developed their own research directions, focusing on implementation various fields biology medicine. The aim this future article is consistently consider most recent advances cell–capsule interactions for different biomedical applications, including functionalization clinically relevant cells, nonviral gene delivery, magnetization cells control movement, vivo drug delivery. Finally, description discussion new trends perspectives improved functionalities design cell-assisted vehicles major topics work.