A Liposome Encapsulated Ruthenium Polypyridine Complex as a Theranostic Platform for Triple-Negative Breast Cancer

• DOI: 10.1021/acs.nanolett.7b00132
• Publication Date: 2017-04-18T19:17:32Z
• Authors: Jianliang Shen; Han-Cheon Kim; Joy Wolfram; Chaofeng Mu; Wei Zhang; Haoran Liu; Yan Xie; Junhua Mai; Hang Zhang; Zhi Li; Maria Guevara; Zong-Wan Mao; Haifa Shen
• Keywords: Triple-negative breast cancer

Ruthenium coordination complexes have the potential to serve as novel theranostic agents for cancer. However, a major limitation in their clinical implementation is effective tumor accumulation. In this study, we developed liposome-based nanodelivery system [Ru(phen)