Electrochemical Oxidative Oxydihalogenation of Alkynes for the Synthesis of α,α-Dihaloketones

• DOI: 10.1021/acs.orglett.0c00052
• Publication Date: 2020-01-14T12:19:50Z
• Authors: Xiangtai Meng; Yu Zhang; Jinyue Luo; Fei Wang; Xiaoji Cao; Shenlin Huang
• Keywords: 01 natural sciences; 0104 chemical sciences

An electrochemical oxydihalogenation of alkynes has been developed for the first time. Using this sustainable protocol, a variety of α,α-dihaloketones can be prepared with readily available CHCl3, CH2Cl2, ClCH2CH2Cl, and CH2Br2 as the halogen source under electrochemical conditions at room temperature.