Copper-Catalyzed Disulfonation of Terminal Alkynes with Sodium Arylsulfinates

• DOI: 10.1021/acs.orglett.0c00575
• Publication Date: 2020-02-26T21:26:39Z
• Authors: Zhenhua Liu; Lin Yang; Kaining Zhang; Wanjiao Chen; Tian Yu; Lianxiao Wang; Wen Gao; Bo Tang
• Keywords: 01 natural sciences; 0104 chemical sciences

A novel and direct disulfonylation reaction of commercially available terminal alkynes under copper(I)/bromodifluoroacetate cocatalyst has been realized. This protocol provides a facile and practical pathway to selectively access (E)-1,2-disulfonylethenes, in which features good functional group compatibility, easily available starting materials, and excellent stereoselectivity with good yields.