Organophotoredox-Catalyzed C–H Functionalizations of Benzophospholes

• DOI: 10.1021/acs.orglett.4c01535
• Publication Date: 2024-06-18T16:24:47Z
• Authors: Yu Tokura; Shibo Xu; Ikki Kamiyoshi; Koji Hirano
• Keywords: Surface Modification; Rose bengal

An organophotoredox-catalyzed oxidative C-H functionalization of benzophospholes has been developed. The alkoxycarbonylation with methyl carbazate occurs in the presence Rose bengal, whereas Eosin Y enables dehydrogenative coupling secondary phosphine oxides and ethers, delivering phosphinylated alkylated products. scope partners is complementary to that conventional metal-promoted activation, thus successfully expanding chemical space substituted phospholes accessed by protocols.